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The Rise of Vertical AI
Where the Next Billion-Dollar Startups Will Come From
Hi friends 👋
A few weeks ago, I was speaking with a founder who had recently shifted his product from a general-purpose AI copilot to a very narrow workflow in healthcare. I asked him what drove the decision.
He paused for a second and said something that stuck with me:
“Horizontal AI is exciting — but vertical AI actually gets used.”
Not “makes more money.”
Not “sounds better in a pitch deck.”
Just gets used.
And the more conversations I had with founders, operators, and investors, the clearer this pattern became:
The biggest wave of real, sustained AI adoption is happening inside industries — not on the surface.

In this week’s deep dive, we’ll explore why vertical AI is gaining momentum, which sectors are shifting the fastest, and how founders can identify the highest-leverage opportunities.
Here’s what you’ll find inside:
What Vertical AI Actually Means — A Clear Definition
Why the Market Is Shifting Toward Vertical Solutions
Industry Breakdown: Where AI Is Creating Real Lift
The Hidden Opportunities Most Founders Miss
The Vertical Wedge Strategy (A Step-by-Step Guide)
A Practical Framework for Founders
Let’s get into it.
— Naseema Perveen
IN PARTNERSHIP WITH DEEPGRAM
Voice AI Goes Mainstream in 2025
Human-like voice agents are moving from pilot to production. In Deepgram’s 2025 State of Voice AI Report, created with Opus Research, we surveyed 400 senior leaders across North America - many from $100M+ enterprises - to map what’s real and what’s next.
The data is clear:
97% already use voice technology; 84% plan to increase budgets this year.
80% still rely on traditional voice agents.
Only 21% are very satisfied.
Customer service tops the list of near-term wins, from task automation to order taking.
See where you stand against your peers, learn what separates leaders from laggards, and get practical guidance for deploying human-like agents in 2025.


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